On this page you can find an overview of the people that are involved in the IMPRESS project.
Dr. Willem Haasnoot (RIKILT Wageningen UR) is a senior scientist with over 30 years of experience on the development of immunoassays in food and feed and he is specialised in the (biosensor) detection of toxins, drug residues and food proteins (such as allergens).
Project role: coordination of the IMPRESS project, advising on immunoassays, supply of reagents (antibodies and conjugates) and short-time secondments to Plasmore.
In June 2004, she obtained the degree in Agricultural Technical Engineering at the University of Almeria for the Specialization in Agricultural and Food Industry. From September 2006 to December 2010, she was working as Laboratory Technician in the research group of Analytical Immunotechnology in the Institute of Agrochemistry and Food Technology (IATA-CSIC) in Valencia. She acquired wide experience in the development and application of immunoanalytical tools like animal immunization, application of hybridoma technology, production and purification of antibodies, characterization of antibodies by ELISA, optimization of immunoassays, extraction and processing of food samples prior to their analysis. In September 2011, she was graduated as Agricultural Engineer at the Polytechnic University of Valencia (Spain). From October 2011 to August 2013, she was working in RIKILT Wageningen UR (Wageningen, The Netherlands) as a member of the Veterinary drugs unit which is devoted to the detection of contaminants and additives in food and feed. In that period, she got a wide experience in the development of multiplexed bioassays using label-free and flow cytometry-based technology biosensors working for several collaborative European projects (RADAR, NANODETECT and CONffIDENCE).
Project role: Laura was seconded from RIKILT Wageningen UR to Schafer-N for 2 periods of 2 months for epitope mapping experiments and to Plasmore for 20 months during which she developed the new 3D chemistry and multiplex immunoassays. After her secondment to Plasmore, which ended in July 2015, she decided not to return to RIKILT and transferred project-relevant knowledge to Willem (written) and to Francesca (practical).
Mr. Arjen Jongebreur (RIKILT) is an experienced financial controller and his constructive contribution was very helpful for the three partners in the project and to coordinate the project during the many changes.
Prof. Franco Marabelli is, since June 2015, the new Scientific Director of Plasmore. Previously he was involved as cofounder of Plasmore (spin-off of the University of Pavia) and as advisor of the activities in the field of nanoplasmonics and device development.
PhD at the Swiss Federal Institute of Technology (ETH)Zurich, since 1992 Associated Professor and since 2011 full professor at the Science Faculty of the University of Pavia. He is responsible for the local Optical Spectroscopy Laboratory; he has been coordinator or local scientific responsible for several different national and international projects.
His main interest is the optical spectroscopy of solid state materials and he has been involved in researches on heavy fermions, silicides and fullerenes and SiGe systems. The recent topic of interest
are photonic crystals and optical response in semiconducting polymers. In collaboration with the Joint Research Centre of the European Commission in Ispra, he began the study of biosensor devices based on plasmonic crystals. He is inventor in 6 patents among which one for an interferometry-based instrument (2003) and three concerning plasmon resonance based biosensitive devices (2010).
Dr. Francesca Carpignano joined Plasmore s.r.l. in June 2015. Since then she is responsible for (re)building the optical instrument for label-free biosensing applications and for fabricating the nanostructured chip, she works also on developing the microfluidics setup and the software for image analysis. She received the Graduate degree (cum laude) in biomedical engineering from the University of Pavia, Italy, in 2010, with a thesis on micro-opto-fluidic devices for photonic crystal biosensors and the Ph.D. degree in bioengineering and bioinformatics from the same university in 2014 with a dissertation on a new 3-D silicon microstructure for simultaneous cell culture and label-free optical transduction. Her current research interests include biosensors, microfluidics, photonic crystals, silicon micromachined devices, lab-on-chip, nanomedicine, and cell culture.
Dr. Gerardo Marchesini was the General Director (2014-2015) of Plasmore and the director for the activities of development of biointerfaces and business developer for the applications of the technology. Gerardo has a PhD in analytical biochemistry and 15 years of experience developing and using biosensing platforms for bioanalysis. Since 2011, he was part of the management team of Plasmore together with Andrea and in 2014 he obtained an Executive MBA degree at the IE business school. He left Plasmore in June 2015 to go back to Argentina where he is an independent consultant in Nano-Biotech Entrepreneurship. He is still involved with Plasmore as an external advisor and, as such, transfers his knowledge to Francesca.
Ana Frangolho Trindade e Silva obtained a degree in chemistry from the University of Coimbra, Portugal, in 2006. During her young career, she worked in research related to protein activity, folding and stability at the Universities of Coimbra and Lisbon, Portugal and of Swansea, Wales, at the Technologie Transfer Zentrum - Bremerhaven, Germany and at the Nanobiosciences Unit of the JRC, Italy. She joined Plasmore Srl in 2010. Since then she was responsible for the development of nanobiointerfaces for biosensing applications working on nanofabrication, surface engineering, bioassay development, optical prototyping, microfluidics, image analysis and software development to set up a portable imaging biosensor. She was seconded to RIKILT for 2 years for the development of applications for the multiplex optical biosensor for the detection of low and high molecular weight food contaminants (antibiotics, mycotoxins and allergens). She left the company in August 2015 to return to Portugal and transferred most of the project-relevant knowledge to Francesca.
Dr. Andrea Valsesia (Plasmore Srl.) has a degree in physics from the University of Pavia (Italy) and a PhD in Nanotechnology obtained from the same University in 2008. During his PhD, he developed a new technique for the fabrication of nanostructured surfaces for advanced bio-interfaces. Between 2003 and 2009, he has been working at the Joint Research Centre of the European Commission in Ispra (Italy) on the development of nanofabrication techniques based on cold plasma processes. In March 2009, he founded the Italian SME Plasmore Srl. and since then he is responsible for nanofabrication and the strategic development of biosensing devices. He is co-inventor of a recent patent, jointly owned by the European Commission and the University of Pavia, on a novel surface plasmon resonance sensing method and system. The IMPRESS project has access to this patented technology.
Project role: advising on nanoplasmonics, nanofabrication and handheld imaging SPR and short-time secondment(s) to RIKILT Wageningen UR. He left the company in 2014 for a position in the Joint Research Centre in Ispra.
Dr. Miguel Manso Silvan of the University in Madrid was employed by Plasmore for 12 months, starting in August 2012, during which he worked on the improvement of the nanostructured sensor chip surface chemistry.
Dr. Claus Schafer Nielsen (Schafer-N) is MD graduated in 1975/76 from The University of Copenhagen and is authorized as specialist in Chemical Pathology. He has more than 30 years of experience in protein and peptide research and is owner of and CEO in Schafer-N Aps.
Project role: advising on the use of the high-density peptide array and the application for epitope mapping.